Global Health Economic Decision Thresholds and Monetary Net Benefit Framework

Reproduce, critically evaluate and extend country-specific health economic decision thresholds and monetary net-benefit methods for global health-system decision making. The project will test sensitivity to alternative health-expenditure definitions, life-expectancy modelling choices, temporal updating, macroeconomic assumptions and uncertainty; outputs will emphasize transparent limitations and appropriate use in resource-allocation decisions.

This project is designed to produce decision-relevant evidence for clinical practice, health-system planning or research. Participation combines applied training, verifiable scientific work and contribution to a publication-quality manuscript.

Reproducible health-economic modelling with traceable inputs, uncertainty analysis, sensitivity analyses and explicit testing of modelling assumptions.

Peer-reviewed literature, public datasets and project-specific verified sources.

Participants will support data provenance, literature review, replication checks, country-level input verification, interpretation and manuscript preparation. Quantitative modelling will be supervised by microscopIA data scientists.

microscopIA is designed so participants can progress at their own pace within project deadlines. Work is primarily asynchronous and there is no fixed weekly schedule. An average commitment of 5–7 hours per week is anticipated and can be distributed flexibly. Mandatory meetings are kept to the minimum necessary. Under a self-governance model, each team may choose to meet more often when that improves coordination. The key expectation is to complete agreed tasks and deadlines to a high standard. The model is designed to remain compatible with medical school, rotations, clinical duties, call schedules and other professional responsibilities.

Economic modelling Sensitivity analysis Data traceability Decision interpretation

microscopIA will provide training in decision-analytic concepts, net monetary benefit, threshold interpretation, uncertainty, reproducibility and country-level data verification.

Expected outputs include a reproducible international threshold dataset, sensitivity analyses, country-level estimates, methodological critique and manuscript intended for a PubMed-indexed journal.

Manuscript intended for submission to a PubMed-indexed journal; preprint whenever appropriate.

Active microscopIA membership is required. Working language: English.

Medical students, junior doctors and early-career professionals interested in Methodological Investigation, with attention to detail, independence and the ability to deliver high-quality work in a flexible environment.

No specific certificate is required. Project-specific onboarding and calibration are mandatory.

microscopIA will cover approved article-processing or publication fees for the anticipated manuscript. Participants will not be required to personally pay approved publication charges. Coverage is subject to the project reaching manuscript quality, compliance with the approved protocol, and submission through the microscopIA research program.

The project is designed to produce a substantive research record and a manuscript intended for submission to a PubMed-indexed journal. Authorship is contribution-based and follows ICMJE criteria: substantial contribution to the work, drafting or critical revision, final approval, and accountability. A preprint will be prepared whenever appropriate. Poster presentation opportunities may be assigned based on project performance and conference fit. Certificates, reference letters and other academic documents remain subject to the applicable microscopIA Membership and Project Terms.

Each participant may declare a maximum of two institutional affiliations. Format: Department, Organization (Hospital, University, Company), City, Country.

Jorge Racedo at microscopIA. Senior clinician or subject-matter expert allocated by microscopIA.